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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a8f6bda5a4177ad723cbf55ce2a985059f48c4f8262c10958f120dd154f44c5' 
  AND token = 'hP5//kx4jAUXsgbLl1ZaaMl7XCdb5/+yTz7MkB1W3OA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}