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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e75d3c6e79592f63c954a2d943a8b6734be9a7497dfc3b54b668760fcd859de' 
  AND token = 'sEnCbWrfjJJ58LhOhdQUIZ89FJ6hdYhD/nAZfPH2lSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}