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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ead32d3e10cbc8b2221c82f414177a9818783edc42ee0381c6175c55b8bacbfc' 
  AND token = 'slxMB8l7I+raMb/5QMTG2Nuj/GBLSBVlFNohra5Sa68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}