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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c84e0544be11734a3cd43bc75dc1c492de9b52b817b778c539314d3ba5fa55' 
  AND token = '5mAlMR0PjR9Pg7lGBhFEdM1yAZDEFp1q1/gxNkXtxf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}