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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3269f52b27114b6e9607aa1122b4b182de4d3358a0fe76a38a17e0eb9a16bc46' 
  AND token = 'j78Av1m3pIJKtCm7pwGId6mGJHzT1FigsHofmswsnXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}