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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c3415f7262d1dbd83170eb07f20310699ef1013f6d0a82afbfe7e78267100a3' 
  AND token = 'ET74TaaJdqXC204IX3OpTo9VRjNRIhP87T1nM/B2EkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}