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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d9043acadc6b536cbb8ac1c49a3bf38f3267e751253443d1727668ab2cc7fb9' 
  AND token = 'tAgLhB5s+hatFXYNTgG8ZNRvNepJBb2FCgE5oeW2S10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}