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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88e3208a34aed3f56b461168241d725214e0795b6b079a6f1ce533cc245384d9' 
  AND token = 'cmNZnPD10trWlS7evJ6Ge20Pe3pdLUHWmVkUUR1Fl3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}