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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '074f1b86d01219cc056a6d1456a0d2a4372476921963a8f0a20860eabd9d5fa1' 
  AND token = '1j9ivQN1TjDZxdldlkzh1fhXFsX4nO4dyFOSFuRf5wQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}