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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de09166811403606584cb6e71fe869bed27bd13691decf120173e0d46c4688b' 
  AND token = 'A4+jkK4GU8dvevyRQVY07TThkZn1WK8y+CcKJ4H7MHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}