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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad0920bb30d81341eeb1e39257149c023c62d3ba38edaf33a73327822585f04f' 
  AND token = 'TBVzDzlQTBO+yNO6YFAJ0B/TKsmZeNb9GI45wQFNNOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}