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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38f2998f1293e3b7e526b8219ca655a8909abc023041b761ec9c100c82bea8b8' 
  AND token = 'wUEaot0paYUkeQHK/skj6J0lKim2jcJa6U7IQ3s8F5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}