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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9e09c01234ca2ffa7f89f0e0d2fdfe0b52b0c713a739898670079a22bf34324' 
  AND token = 'JxUJbMJTyLEdMba+PLZSxNg1Y8rcIkGmtW7/LPcVl9A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}