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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c319b1b835c03a8dc74ec678b14f64cec477de077bee65024ca5d7fbeeb389b2' 
  AND token = 'yntB8qT3g0pS2vhPcRUspAMUrixMG3iZRqQjWSpkcxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}