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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2911fff0a75a0daf4be1ac2dfa66400fdcf5c48c6c84579ca62f0eba1f1433f' 
  AND token = '8bI5LpBVAx2XIIBDZQXCyhjlGv+nHNLCMCaKCoM5uPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}