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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53af405c1da5fda98aac659ed6a608b374fb40aa2fd86212061543cd2abb2fc' 
  AND token = 'THH4Ktuy6D6xi00EZ4HU0u5K7eIVPiTechxOs4cfo0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}