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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ece5e39fb704ba188cdb9ba9de04051032bb5a4dc3e3990635296c87dc1dd2f' 
  AND token = 'Vkbil/TfRaKQA7nvV3TvV1Eqc2+qp0AgrmS8lRQ2hRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}