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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1452fd81d545ef4e3eb4c8c3847a7dc87a0358f7e023cbf280e7e10784338a22' 
  AND token = 'IbKpNiypH1cjmn9pU2Nf3skAKIs5U5Ysldj84YVxwvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}