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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e6ebc0157986d4edaa5d01cf4849723cddf074a767e637bbc43f3f4f8d1067' 
  AND token = 'WkJ2u6oFQry8nCoolumwf5RynQvqxzQR/EIT6aFi+D8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}