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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2df5293d8766e7128ebdc8211a59abec7cbb5f687defb981dceb206d5a78358' 
  AND token = 'QFXTQR2nROapP5hwS9jY8FUeZEGato73Nk9vZ8nDfn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}