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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049db5a1600333c6a6a1c17ec9680e3acf6d48bcb27127923e402cd8529226ec' 
  AND token = 'FCV3W0Cu3GiqWdw523CXWIQaz4jVybFMHmAG/8eN1O4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}