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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60b144b047fff3c8e648fe344fd0263a3b08a8eec0d57f2e2c141da9d4cb7a5c' 
  AND token = 'nr2Nng/RCWETUnjVoXS+lUXKL26k2Z/ZMpUj1lj1b6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}