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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a6c36f6ee6234c909239222706a9282edc8275b47e917b9512784f6dd21d2b5' 
  AND token = 'F0UwEtopdCOShod7HDeedrw8UGTCG4/wUG02YAzTcsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}