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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '253cb6f433eedae022f8422eff961486cbdd6038e3c7bd1b637d561d6307cfe2' 
  AND token = 'DWom4nqPCM8b/rtSMvydRrAUpJEeeWt1huZ4Y3wFo0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}