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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c245dd553179b7a8f698e410efe1dc14cd10753297e7eb31b135b9892016a3e' 
  AND token = 'HJ0ON1oJI4LeISbTmC7JD/H2s9wdxvgFWAZ4lfSa+ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}