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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1648e1f6a98d4b8e5b71353219fcc8027f16f3712778910b1bfc09e25b9c8c9a' 
  AND token = '79dKdKq8xV50klXLM6ZY+F2/QAg1Y1WrsNw3UfczEcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}