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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38106b766996896c08566fa21a1fa37bb35d53253d3fa6a711b2ae14af7f425f' 
  AND token = 'nmI6dqbvsqxV/1+AnLetegVlrdZWn71/5zQ5DxoQm8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}