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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6666b5e43a97cac95815f22ca3dee78a6b5e694d90420eae935dd7b7d07cf61e' 
  AND token = 'D6EZGL+IpH+h9iJXTXfWUyZ+Zg2+USZ/uDj0D8W2Vm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}