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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76728df488d30957e55624f9e23a18f715a26f458fe0ad72027da9d7f8b669f6' 
  AND token = 'Dn6OA4FOfqSxqsjalUlkV+sBZ9updDohnpvLILZWj2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}