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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd8d66e78abe7d4ff244f32af1a0713b765c4260d03ef2a8477da8ab63b182f6' 
  AND token = '7eRpx+FMA9ATAqO8/9lWKDNuhG2lkskSv4I+T5Hfv1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}