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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b8cd9d3bf7bef52b7f514c831f5f202795091789cfca30a330d8bc183431641' 
  AND token = 'IkhCE9d48QBWKw/ZfNZSyPIAg1aHs2NoQ1tc8G2v0j0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}