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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b4c29cb7419b4cfc2e27f16a52b25d454b1d1ac5cb451a15daa2dcafecb05e5' 
  AND token = '9DthAkjSYPKQXON/dUSsEHK8H77sBW5ul1ei/N4mlLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}