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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3af8fce737efec48b58b9c7befc7bd00f8853a383b5c0621b18e010506e936a' 
  AND token = 'efgbfNODZ8wkVY6Lrif+lMmtvylmuJfmIrUlq+2k7Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}