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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1170bb2e10b9676c77cfa10e5982392ac39f72090f7f9fb742c6d4f006c43bb' 
  AND token = '/x/k+yMfYaWD3BSUtoUe+6VQ4nW1MdrjaXbxoSfrLdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00086

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}