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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de8c0cf434b88868d194303b632a5b48394afe43b70b78abff2192e5939daf9b' 
  AND token = 'twQvuw9hlcCgZFrmo5KkkZ6U47qFL0q6PFTSTENsMpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}