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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '113eb7e94c2479a0664b3edb7fc3c467d05cebefa025a4b1b83e886d8f150c4c' 
  AND token = 'oqG+PlYZWVx4sz7P3oGBxz7ohG4SIcC+UDZEQP602Pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}