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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc44daf8124a54c5e3b11752d4a278559f0d32b8c6f7dc82794adf3f037a9a3b' 
  AND token = 'u8ohKhL+ykE/aS+6FgVzaI904ckL1g0mTXDaKpNTjj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}