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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b33c7f087723f746afb16c85aff358d30e3f20af4a78308df056371871fbeb57' 
  AND token = 'Gpg+yRxlrdFSvMwl/xwR315pLWk7m3v9f0dcfM41ics=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}