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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acdc2fe9a48dba8418b6e2d9b5a14ba000b1c6ef681dbe7cfd70526549d79d13' 
  AND token = '69RWzVGKbZD9FWShx2GgeaXL7O4YnDehyLjdm0lTED4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}