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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6936783babac8d3ed862a9d20cb85f9c32a980d1c82d291b0805a546638e5251' 
  AND token = 'cpy4vEzsvpyTiPbo0/ZJn1bnEzlq/hDJL8sk1lT9fNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}