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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ccf1b19f2cd958caa1323cca45ea06acbaa1255d2915a015941a2b8feb3b1d5' 
  AND token = 'HJ6s9yxkSKKK0ol9HOsQra9p/rOcSk8R3pwuDdSxv8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}