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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea0366cb18fc3639d63bd22a59e0345d62de365292aaa1a1cbc64ee475fc4639' 
  AND token = 'TsidAOZfPiTHyu7UzNjn7e1EmbiNNPlRQOZkUUKC7mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}