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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8143bbf0a7e2ab4dceff12e988e47be2622154b29bcc2b6bd2c156cedeea508d' 
  AND token = 'a847FxP+9CRvhcFTKxiC5OqgB1iAMU8qodVud4RxkDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}