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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0118c89563d590a15cd552bedb8f794078f6b9e45a53a3ae601b308625a0995' 
  AND token = 'A0hHlgrIp+HneSkEuCDJgKWLH95y3hwuYlpyLiQ2nxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}