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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0619e8a11ed7d13cc74eb1bce0a09aae67ebb40a64bf01fdcd004b43b0872065' 
  AND token = 'ODQ2aIEP8lx1vYJY/mhC/844bjEfOy/wIDJgRE7uF30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}