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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69173edbeaff485cac65bc82d8b03f7840c2e276ea1ac9752cdb7fdc58d44510' 
  AND token = 'qvenknv2hvXOGyyBpF/vk8chDxMuURZfG4Zw5wndhgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}