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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd227f0fefe213751d27808b634d1af1d3e12397e01cd8d277d4c3aba743059d' 
  AND token = 'uQRRU/7KzEOQOIrfxfdMc0SrVyiXSIwsmRTF+yvD3ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}