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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3c97ebdbf49adc96024097f7e10e7ff4a6a7753010bcc9458d9ea406b160b90' 
  AND token = 'zYe6x7Zwz2/SHEKEApnOU9R4bdVcALjGyHKZy+eAtwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}