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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a43fa8ff6c86ad02ca14cfbf32aeba6fb531e15057677ea428182d099a93a2' 
  AND token = 'o9JkZ9HJ7eq4p5MsSMSqsr0SSngHrdUdwDXMAQ0E/zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}