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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0e2b57ff3c5aedb82e92416d15b32f4054b9ce1c7958cc6c3d80bfa75248795' 
  AND token = 'o6h45E/AddGNqFTSp4G3WMs2eSD385Lo8uSNYrSKsz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}